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The Morphology and Composition of Cholesterol-Rich Micellar Nanostructures Determine Transmembrane Protein (GPCR) Activity

We examined model mixed micelles consisting of the nonionic surfactant n-dodecyl-β-D-maltoside, 3-(3-cholamidopropyl)-dimethylammoniopropane sulfonate, and the cholesterol derivative cholesteryl hemisuccinate (CHS) to identify micellar properties that are correlated with the in vitro conformational...

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Bibliografische gegevens
Hoofdauteurs: O'Malley, Michelle A., Helgeson, Matthew E., Wagner, Norman J., Robinson, Anne S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Biophysical Society 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021673/
https://ncbi.nlm.nih.gov/pubmed/21244820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.12.3698
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