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Detailed Tuning of Structure and Intramolecular Communication Are Dispensable for Processive Motion of Myosin VI
Dimeric myosin VI moves processively hand-over-hand along actin filaments. We have characterized the mechanism of this processive motion by measuring the impact of structural and chemical perturbations on single-molecule processivity. Processivity is maintained despite major alterations in lever arm...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3021667/ https://ncbi.nlm.nih.gov/pubmed/21244839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.11.045 |
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