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Facultative heterochromatin formation at the IL-1 beta promoter in LPS tolerance and sepsis
The clinical phenotype in sepsis that is observed as LPS tolerance is determined by silencing of proinflammatory genes like IL-1 beta (IL-1β). This study shows that facultative heterochromatin (fHC) silences IL-1β expression during sepsis, where we find dephosphorylated histone H3 serine 10 and incr...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3021647/ https://ncbi.nlm.nih.gov/pubmed/21078560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2010.10.007 |
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