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Role of Antibody and Complement in the Immune Clearance and Destruction of Erythrocytes II. MOLECULAR NATURE OF IgG AND IgM COMPLEMENT-FIXING SITES AND EFFECTS OF THEIR INTERACTION WITH SERUM

A model for the immune clearance and destruction of homologous erythrocytes has been further explored. In this model, every IgM anti-erythrocyte antibody molecule in an antibody preparation was shown to fix Cl. About 2000 IgG antibody molecules were required to form a Cl-fixing site on the guinea pi...

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Dettagli Bibliografici
Autori principali: Schreiber, Alan D., Frank, Michael M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1972
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC302164/
https://ncbi.nlm.nih.gov/pubmed/4622104
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