Rise and Fall of an Anti-MUC1 Specific Antibody

BACKGROUND: So far, human antibodies with good affinity and specificity for MUC1, a transmembrane protein overexpressed on breast cancers and ovarian carcinomas, and thus a promising target for therapy, were very difficult to generate. RESULTS: A human scFv antibody was isolated from an immune libra...

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Bibliografiske detaljer
Main Authors: Thie, Holger, Toleikis, Lars, Li, Jiandong, von Wasielewski, Reinhard, Bastert, Gunther, Schirrmann, Thomas, Esteves, Isabel Tourais, Behrens, Christian K., Fournes, Bénédict, Fournier, Nathalie, de Romeuf, Christophe, Hust, Michael, Dübel, Stefan
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021526/
https://ncbi.nlm.nih.gov/pubmed/21264246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015921
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