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Peripheral Aromatic L-Amino Acids Decarboxylase Inhibitor in Parkinsonism. I. EFFECT ON O-METHYLATED METABOLITES OF L-DOPA-2-(14)C

The effects of MK-486, an inhibitor of peripheral aromatic L-amino acids decarboxylase, on the urinary metabolites derived from orally administered L-Dopa-2-(14)C were studied in three Parkinsonian patients. Treatment with MK-486 before L-Dopa-2-(14)C markedly reduced radioactivity found in catechol...

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Udgivet i:J Clin Invest
Principais autores: Messiha, F. S., Hsu, T. H., Bianchine, J. R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1972
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC302144/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5009125/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI106831
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