A multi-gene transcriptional profiling approach to the discovery of cell signature markers

A profile of transcript abundances from multiple genes constitutes a molecular signature if the expression pattern is unique to one cell type. Here we measure mRNA copy numbers per cell by normalizing per million copies of 18S rRNA and identify 6 genes (TIE1, KDR, CDH5, TIE2, EFNA1 and MYO5C) out of...

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Bibliographische Detailangaben
Hauptverfasser: Wada, Youichiro, Li, Dan, Merley, Anne, Zukauskas, Andrew, Aird, William C., Dvorak, Harold F., Shih, Shou-Ching
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Netherlands 2010
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021151/
https://ncbi.nlm.nih.gov/pubmed/20972619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-010-9315-8
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