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Atorvastatin neutralises the thrombin-induced tissue factor expresion in endothelial cells via geranylgeranyl pyrophosphate

Statins may have beneficial effects in atherogenesis given their antithrombotic properties involving non-lipid mechanisms that modify endothelial function of tissue factor induction by thrombin. In this study, we investigate the effect of atorvastatin on tissue factor (TF) activity in thrombin-stimu...

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Bibliografske podrobnosti
Main Authors: Martínez-Sales, Vicenta, Vila, Virtudes, Ferrando, Marcos, Reganon, Edelmiro
Format: Artigo
Jezik:Inglês
Izdano: Springer Netherlands 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021141/
https://ncbi.nlm.nih.gov/pubmed/21052830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-010-9319-4
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