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Revisiting human natural killer cell subset function revealed cytolytic CD56(dim)CD16(+) NK cells as rapid producers of abundant IFN-γ on activation

The two major functions of human natural killer (NK) cells are conventionally associated with distinct cell subsets. Thus, cytolytic activity is mostly confined to the CD56(dim)CD16(+) subset, whereas cytokine production is generally assigned to CD56(bright)CD16(+/−) cells. In this study, we reevalu...

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Detalhes bibliográficos
Main Authors: De Maria, Andrea, Bozzano, Federica, Cantoni, Claudia, Moretta, Lorenzo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021076/
https://ncbi.nlm.nih.gov/pubmed/21187373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012356108
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