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Stromal retinoic acid receptor β promotes mammary gland tumorigenesis

Retinoic acid is a potent differentiation and antiproliferative agent of breast cancer cells, and one of its receptors, retinoic acid receptor β (RARβ), has been proposed to act as a tumor suppressor. In contrast, we report herein that inactivation of Rarb in the mouse results in a protective effect...

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Detalhes bibliográficos
Main Authors: Liu, Xingxing, Nugoli, Mélanie, Laferrière, Julie, Saleh, Sadiq M., Rodrigue-Gervais, Ian G., Saleh, Maya, Park, Morag, Hallett, Michael T., Muller, William J., Giguère, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021047/
https://ncbi.nlm.nih.gov/pubmed/21187396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1011845108
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