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Transfer of palmitate from phospholipids to lipid A in outer membranes of Gram-negative bacteria

Regulated covalent modifications of lipid A are implicated in virulence of pathogenic Gram-negative bacteria. The Salmonella typhimurium PhoP/PhoQ-activated gene pagP is required both for biosynthesis of hepta-acylated lipid A species containing palmitate and for resistance to cationic anti-microbia...

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Detalhes bibliográficos
Main Authors: Bishop, Russell E., Gibbons, Henry S., Guina, Tina, Trent, M.Stephen, Miller, Samuel I., Raetz, Christian R.H.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC302101/
https://ncbi.nlm.nih.gov/pubmed/11013210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdd507
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