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Bile salts sensitize esophageal squamous cells to CD95 (Fas/Apo-1 receptor) mediated apoptosis via a protein trafficking mechanism

INTRODUCTION: The role of non-acidic reflux contents on the pathophysiology of Barrett’s Esophagus remains poorly understood. We hypothesized that esophageal squamous epithelium differs from Barrett’s columnar epithelium in response to bile salts with respect to subsequent changes in the cell surfac...

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Bibliographic Details
Main Authors: Naran, Sanjay, Abrams, Peter, de Oliveira, Pierre Queiroz, Hughes, Steven J.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020985/
https://ncbi.nlm.nih.gov/pubmed/20934723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2010.05.001
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