Up-Regulation of Sonic Hedgehog Contributes to TGF-β1-Induced Epithelial to Mesenchymal Transition in NSCLC Cells

BACKGROUND: Lung cancer, especially non-small cell lung cancer (NSCLC) is the major cause of cancer-related deaths in the United States. The aggressiveness of NSCLC has been shown to be associated with the acquisition of epithelial-to-mesenchymal transition (EMT). The acquisition of EMT phenotype in...

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Main Authors: Maitah, Ma'in Y., Ali, Shadan, Ahmad, Aamir, Gadgeel, Shirish, Sarkar, Fazlul H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020967/
https://ncbi.nlm.nih.gov/pubmed/21249152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016068
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