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Crystal structure of FadR, a fatty acid-responsive transcription factor with a novel acyl coenzyme A-binding fold

FadR is a dimeric acyl coenzyme A (acyl CoA)-binding protein and transcription factor that regulates the expression of genes encoding fatty acid biosynthetic and degrading enzymes in Escherichia coli. Here, the 2.0 Å crystal structure of full-length FadR is described, determined using multi-waveleng...

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Udgivet i:EMBO J
Principais autores: van Aalten, D.M.F., DiRusso, C.C., Knudsen, J., Wierenga, R.K.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2000
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Articles
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC302096/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11013219/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.19.5167
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