Proteins Encoded in Genomic Regions Associated with Immune-Mediated Disease Physically Interact and Suggest Underlying Biology

Genome-wide association studies (GWAS) have defined over 150 genomic regions unequivocally containing variation predisposing to immune-mediated disease. Inferring disease biology from these observations, however, hinges on our ability to discover the molecular processes being perturbed by these risk...

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Main Authors: Rossin, Elizabeth J., Lage, Kasper, Raychaudhuri, Soumya, Xavier, Ramnik J., Tatar, Diana, Benita, Yair, Cotsapas, Chris, Daly, Mark J.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020935/
https://ncbi.nlm.nih.gov/pubmed/21249183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001273
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