Nalaganje...
Membrane Cholesterol Modulates β-Amyloid-dependent Tau Cleavage by Inducing Changes in the Membrane Content and Localization of N-Methyl-d-aspartic Acid Receptors
We have previously shown that β-amyloid (Aβ) treatment resulted in an age-dependent calpain activation leading to Tau cleavage into a neurotoxic 17-kDa fragment in a cellular model of Alzheimer disease. This detrimental cellular response was mediated by a developmentally regulated increase in membra...
Shranjeno v:
| Main Authors: | , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2011
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3020782/ https://ncbi.nlm.nih.gov/pubmed/21047784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.154138 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|