Bifunctional Apoptosis Regulator (BAR), an Endoplasmic Reticulum (ER)-associated E3 Ubiquitin Ligase, Modulates BI-1 Protein Stability and Function in ER Stress

Accumulation of misfolded proteins in the endoplasmic reticulum (ER) causes ER stress and activates inositol-requiring protein-1 (IRE1), among other ER-associated signaling proteins of the unfolded protein response (UPR) in mammalian cells. IRE1 signaling becomes attenuated under prolonged ER stress...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Rong, Juan, Chen, Lili, Toth, Julia I., Tcherpakov, Marianna, Petroski, Matthew D., Reed, John C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2011
Gaiak:
Cell Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020754/
https://ncbi.nlm.nih.gov/pubmed/21068390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.175232
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