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p38 MAPK Activation Is Downstream of the Loss of Intercellular Adhesion in Pemphigus Vulgaris

Pemphigus vulgaris (PV) is a potentially fatal blistering disease characterized by autoantibodies against the desmosomal adhesion protein desmoglein (Dsg) 3. Whether autoantibody steric hindrance or signaling through pathways such as p38 MAPK is primary in disease pathogenesis is controversial. PV m...

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Bibliografiska uppgifter
Huvudupphovsmän: Mao, Xuming, Sano, Yasuyo, Park, Jin Mo, Payne, Aimee S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020736/
https://ncbi.nlm.nih.gov/pubmed/21078676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.172874
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