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Spectroscopic Studies on the [4Fe-4S] Cluster in Adenosine 5′-Phosphosulfate Reductase from Mycobacterium tuberculosis

Mycobacterium tuberculosis adenosine 5′-phosphosulfate reductase (MtAPR) is an iron-sulfur protein and a validated target to develop new antitubercular agents, particularly for the treatment of latent infection. The enzyme harbors a [4Fe-4S](2+) cluster that is coordinated by four cysteinyl ligands,...

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Библиографические подробности
Главные авторы: Bhave, Devayani P., Hong, Jiyoung A., Lee, Michael, Jiang, Wei, Krebs, Carsten, Carroll, Kate S.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020729/
https://ncbi.nlm.nih.gov/pubmed/21075841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.193722
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