Spectroscopic Studies on the [4Fe-4S] Cluster in Adenosine 5′-Phosphosulfate Reductase from Mycobacterium tuberculosis

Mycobacterium tuberculosis adenosine 5′-phosphosulfate reductase (MtAPR) is an iron-sulfur protein and a validated target to develop new antitubercular agents, particularly for the treatment of latent infection. The enzyme harbors a [4Fe-4S](2+) cluster that is coordinated by four cysteinyl ligands,...

Full description

Saved in:
Bibliographic Details
Main Authors: Bhave, Devayani P., Hong, Jiyoung A., Lee, Michael, Jiang, Wei, Krebs, Carsten, Carroll, Kate S.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Enzymology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020729/
https://ncbi.nlm.nih.gov/pubmed/21075841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.193722
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items