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Identification of a new isoform of the human estrogen receptor-alpha (hER-α) that is encoded by distinct transcripts and that is able to repress hER-α activation function 1

A new isoform of the human estrogen receptor-alpha (hER-α) has been identified and characterized. This 46 kDa isoform (hERα46) lacks the N-terminal 173 amino acids present in the previously characterized 66 kDa isoform (hERα66). hERα46 is encoded by a new class of hER-α transcript that lacks the fir...

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Bibliographic Details
Main Authors: Flouriot, Gilles, Brand, Heike, Denger, Stefanie, Metivier, Raphaël, Kos, Martin, Reid, George, Sonntag-Buck, Vera, Gannon, Frank
Format: Artigo
Language:Inglês
Published: Oxford University Press 2000
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC302047/
https://ncbi.nlm.nih.gov/pubmed/10970861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.17.4688
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