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The structure and function of the β2-adaptin appendage domain
The heterotetrameric AP2 adaptor (α, β2, µ2 and σ2 subunits) plays a central role in clathrin-mediated endocytosis. We present the protein recruitment function and 1.7 Å resolution structure of its β2-appendage domain to complement those previously determined for the µ2 subunit and α appendage. Usin...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2000
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC302036/ https://ncbi.nlm.nih.gov/pubmed/10944104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.16.4216 |
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