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HILL COEFFICIENT ANALYSIS OF TRANSMEMBRANE HELIX DIMERIZATION
Here we employ the Hill equation, used broadly to characterize cooperativity in protein-ligand binding, to describe the dimerization of transmembrane (TM) helices in hydrophobic environments. The Hill analysis of wild-type FGFR3 TM domain dimerization gives a Hill coefficient of ~1 for lipid bilayer...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3020080/ https://ncbi.nlm.nih.gov/pubmed/19603128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00232-009-9185-1 |
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