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Host Alternation of Chikungunya Virus Increases Fitness while Restricting Population Diversity and Adaptability to Novel Selective Pressures

The mechanisms by which RNA arboviruses, including chikungunya virus (CHIKV), evolve and maintain the ability to infect vertebrate and invertebrate hosts are poorly understood. To understand how host specificity shapes arbovirus populations, we studied CHIKV populations passaged alternately between...

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Bibliografiska uppgifter
Huvudupphovsmän: Coffey, Lark L., Vignuzzi, Marco
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020036/
https://ncbi.nlm.nih.gov/pubmed/21047966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01918-10
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