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Host Alternation of Chikungunya Virus Increases Fitness while Restricting Population Diversity and Adaptability to Novel Selective Pressures

The mechanisms by which RNA arboviruses, including chikungunya virus (CHIKV), evolve and maintain the ability to infect vertebrate and invertebrate hosts are poorly understood. To understand how host specificity shapes arbovirus populations, we studied CHIKV populations passaged alternately between...

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Detalles Bibliográficos
Main Authors: Coffey, Lark L., Vignuzzi, Marco
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020036/
https://ncbi.nlm.nih.gov/pubmed/21047966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01918-10
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