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Host Alternation of Chikungunya Virus Increases Fitness while Restricting Population Diversity and Adaptability to Novel Selective Pressures

The mechanisms by which RNA arboviruses, including chikungunya virus (CHIKV), evolve and maintain the ability to infect vertebrate and invertebrate hosts are poorly understood. To understand how host specificity shapes arbovirus populations, we studied CHIKV populations passaged alternately between...

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Hlavní autoři: Coffey, Lark L., Vignuzzi, Marco
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020036/
https://ncbi.nlm.nih.gov/pubmed/21047966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01918-10
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