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A Transmembrane Serine Protease Is Linked to the Severe Acute Respiratory Syndrome Coronavirus Receptor and Activates Virus Entry

Spike (S) proteins, the defining projections of the enveloped coronaviruses (CoVs), mediate cell entry by connecting viruses to plasma membrane receptors and by catalyzing subsequent virus-cell membrane fusions. The latter membrane fusion requires an S protein conformational flexibility that is faci...

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Autors principals: Shulla, Ana, Heald-Sargent, Taylor, Subramanya, Gitanjali, Zhao, Jincun, Perlman, Stanley, Gallagher, Tom
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020023/
https://ncbi.nlm.nih.gov/pubmed/21068237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02062-10
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