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The E4orf6/E1B55K E3 Ubiquitin Ligase Complexes of Human Adenoviruses Exhibit Heterogeneity in Composition and Substrate Specificity

Although human adenovirus type 5 (Ad5) has been widely studied, relatively little work has been done with other human adenovirus serotypes. The Ad5 E4orf6 and E1B55K proteins form Cul5-based E3 ubiquitin ligase complexes to degrade p53, Mre11, DNA ligase IV, integrin α3, and almost certainly other t...

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Hlavní autoři: Cheng, Chi Ying, Gilson, Timra, Dallaire, Frédéric, Ketner, Gary, Branton, Philip E., Blanchette, Paola
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020000/
https://ncbi.nlm.nih.gov/pubmed/21068234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01890-10
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