A Dimeric Rep Protein Initiates Replication of a Linear Archaeal Virus Genome: Implications for the Rep Mechanism and Viral Replication

The Rudiviridae are a family of rod-shaped archaeal viruses with covalently closed, linear double-stranded DNA (dsDNA) genomes. Their replication mechanisms remain obscure, although parallels have been drawn to the Poxviridae and other large cytoplasmic eukaryotic viruses. Here we report that a prot...

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Bibliographic Details
Main Authors: Oke, Muse, Kerou, Melina, Liu, Huanting, Peng, Xu, Garrett, Roger A., Prangishvili, David, Naismith, James H., White, Malcolm F.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2011
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019997/
https://ncbi.nlm.nih.gov/pubmed/21068244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01467-10
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