Mutational Analysis of the Transmembrane Helix 2-HAMP Domain Connection in the Escherichia coli Aspartate Chemoreceptor Tar

Transmembrane helix 2 (TM2) of the Tar chemoreceptor undergoes an inward piston-like displacement of 1 to 3 Å upon binding aspartate. This signal is transmitted to the kinase-control module via the HAMP domain. Within Tar, the HAMP domain forms a parallel four-helix bundle consisting of a dimer of t...

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Bibliografiska uppgifter
Huvudupphovsmän: Wright, Gus A., Crowder, Rachel L., Draheim, Roger R., Manson, Michael D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 2011
Ämnen:
Signal Transduction
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019941/
https://ncbi.nlm.nih.gov/pubmed/20870768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00953-10
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