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Region of Difference 2 Contributes to Virulence of Mycobacterium tuberculosis
Mycobacterium bovis BCG strains are live, attenuated vaccines generated through decades of in vitro passage. Because in vitro growth does not select for interaction with the host, it has been hypothesized that genetic loci lost from BCG code for virulence determinants that are dispensable for growth...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3019914/ https://ncbi.nlm.nih.gov/pubmed/20974821 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00824-10 |
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