Identification of Immunodominant Antigens by Probing a Whole Chlamydia trachomatis Open Reading Frame Proteome Microarray Using Sera from Immunized Mice

Chlamydia trachomatis infections can lead to severe chronic complications, including trachoma, ectopic pregnancy, and infertility. The only effective approach to disease control is vaccination. The goal of this work was to identify new potential vaccine candidates through a proteomics approach. We c...

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Bibliographic Details
Main Authors: Cruz-Fisher, Maria I., Cheng, Chunmei, Sun, Guifeng, Pal, Sukumar, Teng, Andy, Molina, Douglas M., Kayala, Matthew A., Vigil, Adam, Baldi, Pierre, Felgner, Philip L., Liang, Xiaowu, de la Maza, Luis M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2011
Subjects:
Microbial Immunity and Vaccines
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019893/
https://ncbi.nlm.nih.gov/pubmed/20956570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00626-10
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