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Effects of low-level lead exposure on pyrimidine 5'-nucleotidase and other erythrocyte enzymes. Possible role of pyrimidine 5'-nucleotidase in the pathogenesis of lead-induced anemia.

Similarities between lead-induced anemia and a new hereditary erythorenzymopathy involving pyrimidine-specific 5'-nucleotidase prompted studies of the effects of lead on this and other erythrocyte enzymes. In vitro incubations of normal mature erythrocytes demonstrated that significant inhibiti...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Paglia, D E, Valentine, W N, Dahlgren, J G
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1975
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC301979/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1184742/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108192
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