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Role of DNA methylation of AHR1 and AHR2 promoters in differential sensitivity to PCBs in Atlantic Killifish, Fundulus heteroclitus

Atlantic killifish (Fundulus heteroclitus) inhabiting the PCB-contaminated Superfund site in New Bedford Harbor (MA, USA) have evolved genetic resistance to the toxic effects of these compounds. They also lack induction of cytochrome P4501A (CYP1A) and other aryl hydrocarbon receptor (AHR)-dependent...

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Main Authors: Aluru, Neelakanteswar, Karchner, Sibel I., Hahn, Mark E.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019765/
https://ncbi.nlm.nih.gov/pubmed/21111492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.aquatox.2010.10.010
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