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Live-cell imaging reveals replication of individual replicons in eukaryotic replication factories

Faithful DNA replication ensures genetic integrity in eukaryotic cells, but it is still obscure how replication is organized in space and time within the nucleus. Using time-lapse microscopy, we have developed a new assay to analyse the dynamics of DNA replication both spatially and temporally in in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kitamura, Etsushi, Blow, J. Julian, Tanaka, Tomoyuki U.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019746/
https://ncbi.nlm.nih.gov/pubmed/16814716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2006.04.041
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