Anti-Inflammatory Benefits of Antibiotic-Induced Neutrophil Apoptosis: Tulathromycin Induces Caspase-3-Dependent Neutrophil Programmed Cell Death and Inhibits NF-κB Signaling and CXCL8 Transcription

Clearance of apoptotic neutrophils is a central feature of the resolution of inflammation. Findings indicate that immuno-modulation and induction of neutrophil apoptosis by macrolide antibiotics generate anti-inflammatory benefits via mechanisms that remain obscure. Tulathromycin (TUL), a new antimi...

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Detalhes bibliográficos
Main Authors: Fischer, Carrie D., Beatty, Jennifer K., Zvaigzne, Cheryl G., Morck, Douglas W., Lucas, Merlyn J., Buret, A. G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019645/
https://ncbi.nlm.nih.gov/pubmed/20956586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01052-10
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