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Short Alkylated Peptoid Mimics of Antimicrobial Lipopeptides
We report the creation of alkylated poly-N-substituted glycine (peptoid) mimics of antimicrobial lipopeptides with alkyl tails ranging from 5 to 13 carbons. In several cases, alkylation significantly improved the selectivity of the peptoids with no loss in antimicrobial potency. Using this technique...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3019626/ https://ncbi.nlm.nih.gov/pubmed/20956607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01080-10 |
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