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Correlated fluorescence and 3D electron microscopy with high sensitivity and spatial precision

Correlative electron and fluorescence microscopy has the potential to elucidate the ultrastructural details of dynamic and rare cellular events, but has been limited by low precision and sensitivity. Here we present a method for direct mapping of signals originating from ∼20 fluorescent protein mole...

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Autores principales: Kukulski, Wanda, Schorb, Martin, Welsch, Sonja, Picco, Andrea, Kaksonen, Marko, Briggs, John A.G.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019550/
https://ncbi.nlm.nih.gov/pubmed/21200030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201009037
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