Anti-PSCA mAbs inhibit tumor growth and metastasis formation and prolong the survival of mice bearing human prostate cancer xenografts

Prostate stem-cell antigen (PSCA) is a cell-surface antigen expressed in normal prostate and overexpressed in prostate cancer tissues. PSCA expression is detected in over 80% of patients with local disease, and elevated levels of PSCA are correlated with increased tumor stage, grade, and androgen in...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Saffran, Douglas C., Raitano, Arthur B., Hubert, Rene S., Witte, Owen N., Reiter, Robert E., Jakobovits, Aya
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 2001
Assuntos:	Biological Sciences
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC30194/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11226295/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.051624698
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