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Potassium channel blocker, 4-Aminopyridine-3-Methanol, restores axonal conduction in spinal cord of an animal model of multiple sclerosis

Multiple sclerosis (MS) is a severely debilitating neurodegenerative diseases marked by progressive demyelination and axonal degeneration in the CNS. Although inflammation is the major pathology of MS, the mechanism by which it occurs is not completely clear. The primary symptoms of MS are movement...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Leung, Gary, Sun, Wenjing, Brookes, Sarah, Smith, Daniel, Shi, Riyi
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019253/
https://ncbi.nlm.nih.gov/pubmed/21093437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2010.11.004
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