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Ribonucleotide reduction - horizontal transfer of a required function spans all three domains

BACKGROUND: Ribonucleotide reduction is the only de novo pathway for synthesis of deoxyribonucleotides, the building blocks of DNA. The reaction is catalysed by ribonucleotide reductases (RNRs), an ancient enzyme family comprised of three classes. Each class has distinct operational constraints, and...

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Main Authors: Lundin, Daniel, Gribaldo, Simonetta, Torrents, Eduard, Sjöberg, Britt-Marie, Poole, Anthony M
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019208/
https://ncbi.nlm.nih.gov/pubmed/21143941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-10-383
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