Epigenetic regulation of glial fibrillary acidic protein by DNA methylation in human malignant gliomas

Glial fibrillary acidic protein (GFAP) is an intermediate filament expressed in glial cells that stabilizes and maintains the cytoskeleton of normal astrocytes. In glial tumors, GFAP expression is frequently lost with increasing grade of malignancy, suggesting that GFAP is important for maintaining...

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Autors principals: Restrepo, Andres, Smith, Christian A., Agnihotri, Sameer, Shekarforoush, Maryam, Kongkham, Paul N., Seol, Ho Jun, Northcott, Paul, Rutka, James T.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2011
Matèries:
Basic and Translational Investigations
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018916/
https://ncbi.nlm.nih.gov/pubmed/21075782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noq145
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