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Angiotensin-(1–7) infusion is associated with increased blood pressure and adverse cardiac remodelling in rats with subtotal nephrectomy

ACE (angiotensin-converting enzyme) 2 is expressed in the heart and kidney and metabolizes Ang (angiotensin) II to Ang-(1–7) a peptide that acts via the Ang-(1–7) or mas receptor. The aim of the present study was to assess the effect of Ang-(1–7) on blood pressure and cardiac remodelling in a rat mo...

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Bibliographic Details
Main Authors: Velkoska, Elena, Dean, Rachael G., Griggs, Karen, Burchill, Luke, Burrell, Louise M.
Format: Artigo
Language:Inglês
Published: Portland Press Ltd. 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018845/
https://ncbi.nlm.nih.gov/pubmed/21091432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20100280
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