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Toxicity of depleted uranium complexes is independent of p53 activity

The p53 tumor suppressor protein is one of the key checkpoints in cellular response to a variety of stress mechanisms, including exposure to various toxic metal complexes. Previous studies have demonstrated that arsenic and chromium complexes are able to activate p53, but there is a dearth of data i...

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Hlavní autoři: Heintze, Ellie, Aguilera, Camille, Davis, Malia, Fricker, Avery, Li, Qiang, Martinez, Jesse, Gage, Matthew J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018829/
https://ncbi.nlm.nih.gov/pubmed/21194611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2010.10.010
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