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Krüppel-Like Factor-4 Transcriptionally Regulates VE-cadherin Expression and Endothelial Barrier Function

RATIONALE: Vascular endothelial (VE)-cadherin localized at adherens junctions (AJs) regulates endothelial barrier function. As WNT (wingless) signaling-induced activation of the transcription factor Krüppel-like factor-4 (KLF4) may have an important role in mediating the expression of VE-cadherin an...

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Detalhes bibliográficos
Main Authors: Cowan, Colleen E., Kohler, Erin E., Dugan, Tracey A., Mirza, M. Kamran, Malik, Asrar B., Wary, Kishore K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018700/
https://ncbi.nlm.nih.gov/pubmed/20724706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.110.219592
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