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Cellular Senescence as a Target in Cancer Control

Somatic cells show a spontaneous decline in growth rate in continuous culture. This is not related to elapsed time but to an increasing number of population doublings, eventually terminating in a quiescent but viable state termed replicative senescence. These cells are commonly multinucleated and do...

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Detalhes bibliográficos
Main Authors: Vergel, Mar, Marin, Juan J., Estevez, Purificacion, Carnero, Amancio
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE-Hindawi Access to Research 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018654/
https://ncbi.nlm.nih.gov/pubmed/21234095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/725365
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