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Leptin Receptor-induced STAT3-Independent Signaling Pathways are Protective against Atherosclerosis in a Murine Model of Obesity and Hyperlipidemia

AIMS: Leptin is an adipocyte-derived hormone that has been shown to exert both beneficial metabolic effects and potentially adverse vascular effects in preclinical studies. The primary aim of this study was to determine the effects of leptin receptor signaling pathways on atherosclerosis in the sett...

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Detalhes bibliográficos
Main Authors: Luo, Wei, Bodary, Peter F., Shen, Yuechun, Wickenheiser, Kevin J., Öhman, Miina K., Guo, Chiao, Bahrou, Kristina L., Myers, Martin G., Eitzman, Daniel T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018566/
https://ncbi.nlm.nih.gov/pubmed/21067751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2010.10.009
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