A Two-Way Communication between Microglial Cells and Angiogenic Sprouts Regulates Angiogenesis in Aortic Ring Cultures

BACKGROUND: Myeloid cells have been associated with physiological and pathological angiogenesis, but their exact functions in these processes remain poorly defined. Monocyte-derived tissue macrophages of the CNS, or microglial cells, invade the mammalian retina before it becomes vascularized. Recent...

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Main Authors: Rymo, Simin F., Gerhardt, Holger, Wolfhagen Sand, Fredrik, Lang, Richard, Uv, Anne, Betsholtz, Christer
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018482/
https://ncbi.nlm.nih.gov/pubmed/21264342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015846
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