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Association of the rs738409 polymorphism in PNPLA3 with liver damage and the development of nonalcoholic fatty liver disease

BACKGROUND: In a genome-wide association scan, the single-nucleotide polymorphism (SNP) rs738409 in the patatin-like phospholipase 3 gene (PNPLA3) was strongly associated with increased liver fat content. We investigated whether this SNP is associated with the occurrence and progression of nonalcoho...

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Hlavní autoři: Hotta, Kikuko, Yoneda, Masato, Hyogo, Hideyuki, Ochi, Hidenori, Mizusawa, Seiho, Ueno, Takato, Chayama, Kazuaki, Nakajima, Atsushi, Nakao, Kazuwa, Sekine, Akihiro
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018434/
https://ncbi.nlm.nih.gov/pubmed/21176169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-11-172
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