Polymorphisms in thrombophilia and renin–angiotensin system pathways, preterm delivery, and evidence of placental hemorrhage

OBJECTIVE: To analyze functional polymorphisms in candidate genes (methylenetetrahydrofolate reductase (MTHFR)677C>T, MTHFR1298A>C, Factor 5 1691G>A (FVL), and angiotensinogen (AGT)-6G>A) in relation to a hypothesized placental hemorrhage pathway to preterm delivery (PTD). STUDY DESIGN:...

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Main Authors: Gargano, Julia Warner, Holzman, Claudia B., Senagore, Patricia K., Reuss, M. Lynne, Pathak, Dorothy R., Friderici, Karen H., Jernigan, Katherine, Fisher, Rachel
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018335/
https://ncbi.nlm.nih.gov/pubmed/19733287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2009.05.060
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