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Evolution, genomic analysis, and reconstruction of isobutanol tolerance in Escherichia coli

Escherichia coli has been engineered to produce isobutanol, with titers reaching greater than the toxicity level. However, the specific effects of isobutanol on the cell have never been fully understood. Here, we aim to identify genotype–phenotype relationships in isobutanol response. An isobutanol-...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Atsumi, Shota, Wu, Tung-Yun, Machado, Iara M P, Huang, Wei-Chih, Chen, Pao-Yang, Pellegrini, Matteo, Liao, James C
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018172/
https://ncbi.nlm.nih.gov/pubmed/21179021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2010.98
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