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Evolution, genomic analysis, and reconstruction of isobutanol tolerance in Escherichia coli

Escherichia coli has been engineered to produce isobutanol, with titers reaching greater than the toxicity level. However, the specific effects of isobutanol on the cell have never been fully understood. Here, we aim to identify genotype–phenotype relationships in isobutanol response. An isobutanol-...

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Detalhes bibliográficos
Main Authors: Atsumi, Shota, Wu, Tung-Yun, Machado, Iara M P, Huang, Wei-Chih, Chen, Pao-Yang, Pellegrini, Matteo, Liao, James C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018172/
https://ncbi.nlm.nih.gov/pubmed/21179021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2010.98
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