A comprehensive map of the mTOR signaling network

The mammalian target of rapamycin (mTOR) is a central regulator of cell growth and proliferation. mTOR signaling is frequently dysregulated in oncogenic cells, and thus an attractive target for anticancer therapy. Using CellDesigner, a modeling support software for graphical notation, we present her...

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Bibliografske podrobnosti
Main Authors: Caron, Etienne, Ghosh, Samik, Matsuoka, Yukiko, Ashton-Beaucage, Dariel, Therrien, Marc, Lemieux, Sébastien, Perreault, Claude, Roux, Philippe P, Kitano, Hiroaki
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2010
Teme:
Review Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018167/
https://ncbi.nlm.nih.gov/pubmed/21179025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2010.108
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